Article
On the rate of translocation in vitro and kinetics in vivo of the major oxysterols in human circulation
27 Nov 2002
Abstract excerpt
Oxysterols possess powerful biological activities. Some of their effects on the regulation of key enzymes are similar to those of cholesterol, but are much more potent. One of the critical properties of oxysterols is their ability to pass lipophilic membranes at a high rate. Transfer of unesterified 25-hydroxycholesterol from red blood cells to plasma has been reported to occur more than 1,000 times faster than...
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