Article
Association between apolipoprotein E phenotype and endogenous cholesterol synthesis as measured by deuterium uptake.
Cardiovascular research - 1 Mar 1991
Roe R P, Jones P J, Frohlich J J, Schoeller D A
Abstract excerpt
STUDY OBJECTIVE: The aim was to determine if central pool cholesterol formation rate is related to apo E phenotype in healthy normolipidaemic males. DESIGN: Subjects consumed a fixed composition diet for 5 d and at 07:00 hours on d 5 drank 0.7 g deuterium oxide (D2O).kg-1 body water. Over d 5 body water deuterium enrichment was maintained by ingestion of labelled drinking water. The fractional synthetic rate of...
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