The influence of placental metabolism on fatty acid transfer to the fetus

Abstract excerpt

The factors determining fatty acid transfer across the placenta are not fully understood. This study used a combined experimental and computational modeling approach to explore placental transfer of nonesterified fatty acids and identify the rate-determining processes. Isolated perfused human placenta was used to study the uptake and transfer of 13 C-fatty acids and the release of endogenous fatty acids. Only 6.2...

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