Article
Interleukin-1B 31 C>T polymorphism combined with Helicobacter pylori-modified gastric cancer susceptibility: evidence from 37 studies.
Journal of cellular and molecular medicine - 1 Mar 2016
Ying Hua-Yong, Yu Bei-Wei, Yang Zong, Yang Shan-Shan, Bo Li-Hong, Shan Xiao-Yun, Wang Hui-Jiao, Zhu Yi-Jun, Wu Xue-Song
Abstract excerpt
Gastric cancer is one of the most common malignancies worldwide. Interleukin-1-beta (IL-1β) is a pro-inflammatory cytokine and potent inhibitor of gastric acid secretion. Some studies provided evidence of the association between IL-1B 31 polymorphism and gastric cancer risk while other studies did not. Therefore, we conducted a comprehensive meta-analysis to reassess the association. A systematic literature...
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