Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Base Composition of Mononucleotide Runs Affects DNA Polymerase Slippage and Removal of Frameshift Intermediates by Mismatch Repair in <i>Saccharomyces cerevisiae</i>

21 Nov 2002

Abstract excerpt

The postreplicative mismatch repair (MMR) system is important for removing mutational intermediates that are generated during DNA replication, especially those that arise as a result of DNA polymerase slippage in simple repeats. Here, we use a forward mutation assay to systematically examine the accumulation of frameshift mutations within mononucleotide runs of variable composition in wild-type and MMR-defective...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to DNA Repair Mechanisms
Share to Genetic factors in colorectal cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12446792
DOI: 10.1128/mcb.22.24.8756-8762.2002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Base Composition of Mononucleotide Runs Affects DNA Polymerase Slippage and Removal of Frameshift Intermediates by Mismatch Repair in <i>Saccharomyces cerevisiae</i>PMID 12446792Read ↗

Sequence composition and context effects on the generation and repair of frameshift intermediates in mononucleotide runs in Saccharomyces cerevisiae.Semantic proximity Read ↗

Frameshift mutagenesis: the roles of primer-template misalignment and the nonhomologous end-joining pathway in Saccharomyces cerevisiae.Semantic proximity Read ↗

The role of mismatch repair in the prevention of base pair mutations in <i>Saccharomyces cerevisiae</i>Semantic proximity Read ↗

Hypermutability of Homonucleotide Runs in Mismatch Repair and DNA Polymerase Proofreading Yeast MutantsSemantic proximity Read ↗

A DNA polymerase epsilon mutant that specifically causes +1 frameshift mutations within homonucleotide runs in yeast.Semantic proximity Read ↗

Novel PMS1 alleles preferentially affect the repair of primer strand loops during DNA replication.Semantic proximity Read ↗

Genetic factors affecting the impact of DNA polymerase delta proofreading activity on mutation avoidance in yeast.Semantic proximity Read ↗

8-Oxoguanine incorporation into DNA repeats in vitro and mismatch recognition by MutSSemantic proximity Read ↗

Removal of frameshift intermediates by mismatch repair proteins in Saccharomyces cerevisiae.Semantic proximity Read ↗

Reconstitution of long and short patch mismatch repair reactions using <i>Saccharomyces cerevisiae</i> proteinsSemantic proximity Read ↗

Mutation at a distance caused by homopolymeric guanine repeats in Saccharomyces cerevisiae.Semantic proximity Read ↗

Altered replication and inverted repeats induce mismatch repair-independent recombination between highly diverged DNAs in yeast.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.