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Article

IL-4 increases GABAergic phenotype in rat retinal cell cultures: involvement of muscarinic receptors and protein kinase C.

Journal of neuroimmunology - 1 Dec 2002

Sholl-Franco Alfred, Marques Patrícia M B, Ferreira Cecília M C, de Araujo Elizabeth G

Abstract excerpt

Interleukin-4 (IL-4) is an anti-inflammatory cytokine. During injuries, infections and neurodegenerative diseases, high levels of this molecule are expressed in the brain. In the present work, we investigated the effect of IL-4 on GABAergic differentiation of retinal cells kept in vitro. We analyzed either the uptake of [3H]-gamma-aminobutyric acid (GABA) or the expression of glutamic acid decarboxylase (GAD-67)...

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Source

Identifiers

PMID: 12446004
DOI: 10.1016/s0165-5728(02)00327-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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