Article
Retinal ganglion cell depletion alters the phenotypic expression of GABA and GAD in the rat retina.
The European journal of neuroscience - 1 Sept 1997
Yamasaki E N, Andrade da Costa B L, Barbosa V D, Hokoç J N
Abstract excerpt
We have looked at the phenotypic expression of gamma-aminobutyric acid (GABA) and the two isoforms of its synthetic enzyme [glutamic acid decarboxylase (GAD)-65 and -67] in adult rat retinas that had the superior colliculus, pretectum and optic tract lesioned unilaterally at birth. It has been shown previously that this type of manipulation induces retrograde degeneration of retinal ganglion cells presumably...
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