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Article

Transcriptional activation of the c-fos gene by a LIM protein, Hic-5.

Biochemical and biophysical research communications - 6 Dec 2002

Kim-Kaneyama Joo ri, Shibanuma Motoko, Nose Kiyoshi

Abstract excerpt

Hic-5 is a member of LIM family proteins with a striking similarity to paxillin and localizes primarily in the focal adhesion. We recently reported that Hic-5 translocated to the nucleus under oxidative stress and was involved in transcriptional regulation. In the present study, we extended these findings to show that transcription of c-fos gene was up-regulated by overexpression of Hic-5. In clonal stable...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12445807
DOI: 10.1016/s0006-291x(02)02644-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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