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Article

Transgenic zebrafish model of neurodegeneration.

Journal of neuroscience research - 15 Dec 2002

Tomasiewicz Henry G, Flaherty Denise B, Soria J P, Wood John G

Abstract excerpt

In Alzheimer's disease (AD), the microtubule-associated protein, tau, is compromised in its normal association with microtubules and forms into paired helical filaments (PHF) that are the hallmark cytoskeletal pathology of the disease. Several posttranslational modifications of tau including phosphorylation have been implicated in AD pathogenesis. In addition, and importantly, mutations in the genes encoding...

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PMID: 12444595
DOI: 10.1002/jnr.10451

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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