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Transgenic zebrafish models of neurodegenerative diseases.

Brain structure & function - 1 Mar 2010

Sager Jonathan J, Bai Qing, Burton Edward A

Abstract excerpt

Since the introduction of the zebrafish as a model for the study of vertebrate developmental biology, an extensive array of techniques for its experimental manipulation and analysis has been developed. Recently it has become apparent that these powerful methodologies might be deployed in order to elucidate the pathogenesis of human neurodegenerative diseases and to identify candidate therapeutic approaches. In...

Topics

Animals
Animals, Genetically Modified
Disease Models, Animal
Genetic Predisposition to Disease
Humans
Huntington Disease
Molecular Biology
Motor Neuron Disease
Neurodegenerative Diseases
Phenotype
Tauopathies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Zebrafish

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Identifiers

PMID: 20162303
DOI: 10.1007/s00429-009-0237-1

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