Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human CD25+CD4+ T Suppressor Cell Clones Produce Transforming Growth Factor β, but not Interleukin 10, and Are Distinct from Type 1 T Regulatory Cells

11 Nov 2002

Abstract excerpt

T regulatory (Tr) cells are essential for the induction of peripheral tolerance. Several types of Tr cells exist, including CD4(+) T cells which express CD25 constitutively and suppress immune responses via direct cell-to-cell interactions, and type 1 T regulatory (Tr1) cells, which function via secretion of interleukin (IL)-10 and transforming growth factor (TGF)-beta. The relationship between CD25(+)CD4(+) T...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CAR-T cell therapy research
Share to Immune Cell Function and Interaction
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12438424
DOI: 10.1084/jem.20021139

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human CD25+CD4+ T Suppressor Cell Clones Produce Transforming Growth Factor β, but not Interleukin 10, and Are Distinct from Type 1 T Regulatory CellsPMID 12438424Read ↗

Type 1 T-regulatory cells: their role in the control of immune responses.Semantic proximity Read ↗

Functional features of human CD25+ regulatory thymocytes.Semantic proximity Read ↗

Comparative study of regulatory T cell function of human CD25CD4 T cells from thymocytes, cord blood, and adult peripheral blood.Semantic proximity Read ↗

CD4+CD25+-regulatory T cells from mouse to man.Semantic proximity Read ↗

CD4+CD25+ regulatory T cells: I. Phenotype and physiology.Semantic proximity Read ↗

Control of autoimmunity by naturally arising regulatory CD4+ T cells.Semantic proximity Read ↗

CD4(+)CD25(+) regulatory T cells in rheumatoid arthritis: differences in the presence, phenotype, and function between peripheral blood and synovial fluid.Semantic proximity Read ↗

CD4+ CD25+ CD62+ T-regulatory cell subset has optimal suppressive and proliferative potential.Semantic proximity Read ↗

Functional characterisation of human CD4+CD25+ regulatory T cells and the transcriptional regulator, FOXP3Semantic proximity Read ↗

T regulatory cells control T‐cell proliferation partly by the release of soluble CD25 in patients with B‐cell malignanciesSemantic proximity Read ↗

Human CD4 + HLA‐G + regulatory T cells are potent suppressors of graft‐versus‐host disease in vivoSemantic proximity Read ↗

Antigen-induced IL-10+ regulatory T cells are independent of CD25+ regulatory cells for their growth, differentiation, and function.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.