Article
Influence of the Anx7 (+/-) knockout mutation and fasting stress on the genomics of the mouse adrenal gland.
Annals of the New York Academy of Sciences - 1 Oct 2002
Srivastava Meera, Kumar Preeti, Leighton Ximena, Glasman Mirta, Goping Gertrude, Eidelman Ofer, Pollard Harvey B
Abstract excerpt
The Anx7 gene codes for a Ca(2+)/GTPase with calcium channel and membrane fusion properties that has been proposed to regulate exocytotic secretion in chromaffin and other cell types. We have previously reported that the homozygous Anx7 (+/-) knockout mouse has an embryonically lethal phenotype. However, the viable heterozygous Anx7 (+/-) mouse displays a complex phenotype that includes adrenal gland hypertrophy,...
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