Article
Abnormal movements and tardive dyskinesia in smokers and nonsmokers with schizophrenia genotyped for cytochrome P450 2D6.
Pharmacotherapy - 1 Nov 2002
Ellingrod Vicki L, Schultz Susan K, Arndt Stephan
Abstract excerpt
STUDY OBJECTIVE: To investigate the relationships between cytochrome P450 (CYP) 2D6 genotype, antipsychotic drug exposure, abnormal movements and tardive dyskinesia, and cigarette smoking. DESIGN: Prospective, longitudinal study. SETTING: University mental health research center. PATIENTS: Thirty-seven patients with schizophrenia. INTERVENTION: Patients were genotyped for CYP2D6*1, *3, and *4 alleles, and data...
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