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Article

Glu496Ala polymorphism of human P2X7 receptor does not affect its electrophysiological phenotype.

American journal of physiology. Cell physiology - 1 Mar 2003

Boldt Wolfgang, Klapperstück Manuela, Büttner Cora, Sadtler Sven, Schmalzing Günther, Markwardt Fritz

Abstract excerpt

A glutamate to alanine exchange at amino acid position 496 of the human P2X(7) receptor was recently shown to be associated with a loss of function in human B lymphocytes in terms of ATP-induced ethidium(+) uptake, Ba(2+) influx, and induction of apoptosis (Gu BJ, Zhang WY, Worthington RA, Sluyter R, Dao-Ung P, Petrou S, Barden JA, and Wiley JS. J Biol Chem 276: 11135-11142, 2001). Here we analyzed the effect of...

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Identifiers

PMID: 12431909
DOI: 10.1152/ajpcell.00042.2002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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