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Article

GSTT1 null genotype increases risk of premenopausal breast cancer.

Cancer letters - 8 Jul 2002

Matheson Melanie C, Stevenson Trevor, Akbarzadeh Shiva, Propert David N

Abstract excerpt

The NAT2, GSTM1 and GSTT1 genes are known candidate cancer susceptibility markers and have been investigated in breast cancer susceptibility with conflicting results. We conducted a case-control study to investigate the role of NAT2, GSTM1 and GSTT1 in premenopausal breast cancer. Women with the GSTT1 null genotype were found to have a significant 3.15-fold increased risk of breast cancer (95% CI = 1.7-5.8),...

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Source

Identifiers

PMID: 12430181
DOI: 10.1016/s0304-3835(02)00046-0

Genes

GSTT1
GSTM1
NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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