Article
Retinoic acid isomers produce malformations in postembryonic development of the Japanese flounder, Paralichthys olivaceus.
Zoological science - 1 Oct 2002
Haga Yutaka, Suzuki Tohru, Takeuchi Toshio
Abstract excerpt
We previously reported that characteristic deformities were induced by retinoic acid (RA) treatment of the Japanese flounder, Paralichthys olivaceus, at 6-9 days post-hatching (dph). To evaluate the toxic potency of nuclear retinoid receptors in induction of deformities by RA, we here investigated the effects of retinoic acid isomers on postembryonic development of this species. Larvae were exposed to either 25...
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