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Article

Alteration of cell wall composition leads to amphotericin B resistance in Aspergillus flavus.

Microbiology and immunology - 1 Jan 1999

Seo K, Akiyoshi H, Ohnishi Y

Abstract excerpt

An amphotericin B (AmB)-resistant mutant was isolated from a wild-type AmB-susceptible strain of Aspergillus flavus by serial transfer of conidia on agar plates containing stepwise increased concentrations of AmB up to 100 microg ml-1. The acquired resistance of mycelia was specific for polyene-antibiotics AmB, nystatin and trichomycin. Spheroplasts derived from the resistant mycelia were as susceptible to AmB as...

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PMID: 10609611
DOI: 10.1111/j.1348-0421.1999.tb01231.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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