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Article

Mycobacterium tuberculosis RuvA induces two distinct types of structural distortions between the homologous and heterologous Holliday junctions.

Biochemistry - 13 Jan 2009

Khanduja Jasbeer Singh, Tripathi Pankaj, Muniyappa K

Abstract excerpt

A central step in the process of homologous genetic recombination is the strand exchange between two homologous DNA molecules, leading to the formation of the Holliday junction intermediate. Several lines of evidence, both in vitro and in vivo, suggest a concerted role for the Escherichia coli RuvABC protein complex in the process of branch migration and the resolution of the Holliday junctions. A number of...

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Identifiers

PMID: 19072585
DOI: 10.1021/bi8016526

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Mycobacterium tuberculosis RuvA induces two distinct types of structural distortions between the homologous and heterologous Holliday junctions.PMID 19072585Read ↗

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Formation of a stable RuvA protein double tetramer is required for efficient branch migration in vitro and for replication fork reversal in vivo.Semantic proximity Read ↗

The RuvABC resolvase is indispensable for recombinational repair in sbcB15 mutants of Escherichia coli.Semantic proximity Read ↗

The RuvAB branch migration translocase and RecU Holliday junction resolvase are required for double-stranded DNA break repair in Bacillus subtilis.Semantic proximity Read ↗

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Resolution of joint molecules by RuvABC and RecG following cleavage of the Escherichia coli chromosome by EcoKI.Semantic proximity Read ↗

Abortive recombination in Escherichia coli ruv mutants blocks chromosome partitioning.Semantic proximity Read ↗

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