Article
HTL1 encodes a novel factor that interacts with the RSC chromatin remodeling complex in Saccharomyces cerevisiae.
Molecular and cellular biology - 1 Dec 2002
Romeo Martin J, Angus-Hill Melinda L, Sobering Andrew K, Kamada Yoshiaki, Cairns Bradley R, Levin David E
Abstract excerpt
RSC is an essential chromatin remodeling complex in Saccharomyces cerevisiae that performs central roles in transcriptional regulation and cell cycle progression. Here we identify Htl1 as a novel factor that associates with the RSC complex both physically and functionally. We isolated HTL1 through a genetic screen for mutants that displayed additive growth defects with a conditional mutation in the protein kinase...
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