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Article

A novel gene, Pog, is necessary for primordial germ cell proliferation in the mouse and underlies the germ cell deficient mutation, gcd.

Human molecular genetics - 15 Nov 2002

Agoulnik Alexander I, Lu Baisong, Zhu Qichao, Truong Cavatina, Ty Maria T, Arango Nelson, Chada Kiran K, Bishop Colin E

Abstract excerpt

Primordial germ cells (PGCs) are the precursor of the germ cells in adult gonads. They arise extra-gonadally and migrate through somatic tissues to the presumptive genital ridges, where they proliferate and differentiate into oogonia or spermatogonia cells. Abnormalities in this developmental pro...

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Identifiers

PMID: 12417526
DOI: 10.1093/hmg/11.24.3047

Genes

PGC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12417526-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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A novel gene, Pog, is necessary for primordial germ cell proliferation in the mouse and underlies the germ cell deficient mutation, gcd.PMID 12417526Read ↗

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