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Article

Anti-HIV-1 property of trichosanthin correlates with its ribosome inactivating activity.

FEBS letters - 6 Nov 2002

Wang Jian Hua, Nie Hui Ling, Tam Siu Cheung, Huang Hai, Zheng Yong Tang

Abstract excerpt

Trichosanthin (TCS) is a type I ribosome inactivating (RI) protein possessing anti-tumor and antiviral activity, including human immunodeficiency virus (HIV). The mechanism of these actions is not entirely clear, but is generally attributed to its RI property. In order to study the relationship between the anti-HIV-1 activity of TCS and its RI activity, three TCS mutants with different RI activities were...

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PMID: 12417329
DOI: 10.1016/s0014-5793(02)03539-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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