Article
Expression of recombinant trichosanthin, a ribosome-inactivating protein, in transgenic tobacco.
Journal of biotechnology - 17 Jul 2002
Krishnan Rajesh, McDonald Karen A, Dandekar Abhaya M, Jackman Alan P, Falk Bryce
Abstract excerpt
Trichosanthin (TCS) is an antiviral plant defense protein, classified as a type-I ribosome-inactivating protein, found in the root tuber and leaves of the medicinal plant Trichosanthes kirilowii. It is processed from a larger precursor protein, containing a 23 amino acid amino (N)-terminal sequence (pre sequence) and a 19 amino acid carboxy (C)-terminal extension (pro sequence). Various constructs of the TCS gene...
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