Article
Platelet PlA2 polymorphism and platelet activation are associated with increased troponin I release after cardiopulmonary bypass.
Anesthesiology - 1 Nov 2002
Rinder Christine S, Mathew Joseph P, Rinder Henry M, Greg Howe J, Fontes Manuel, Crouch Jill, Pfau Stephen, Patel Parag, Smith Brian R
Abstract excerpt
BACKGROUND: The PlA2 polymorphism of platelet glycoprotein IIIa has been identified as a prothrombotic risk factor in a number of cardiovascular settings. The aim of this study was to determine whether the PlA2 polymorphism of platelet glycoprotein IIIa and degree of platelet activation were associated with more severe myocardial injury as indicated by troponin I release following cardiopulmonary bypass. METHODS:...
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