Article
[At last, an effective therapy for non-differentiated GI sarcomas (gastro intestinal stromal tumor)].
Journal de chirurgie - 1 Oct 2002
Des Guetz G, De Mestier Ph, Pierga Jean-Yves
Abstract excerpt
Gastrointestinal stromal tumors (GISTs) are non differentiated sarcoma of the gastrointestinal tract and have for a long time been confused with well differentiated tumors and classified as leiomyosarcoma. These tumors are characterized immunohistochemically by CD 117 staining. This marker represents the expression of c-kit which is a receptor for growth factor with enzymatic activity (tyrosine kinase). Recent...
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