Article
[Gastrointestinal stromal tumors].
Praxis - 10 Jan 2007
Hohenberger P
Abstract excerpt
Gastro-intestinal stromal tumors (GIST), an abdominal sarcoma entity are characterized by a gain-of-function mutation in c-kit proto-oncogen (CD117). Initial treatment should aim at complete removal of the primary tumor (R0 resection) which almost never develops lymphatic metastases. Distant metastatic spread involves mainly the peritoneal cavity and the liver. In patients with metastatic disease, treatment with...
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