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Article

Pho85 phosphorylates the Glc7 protein phosphatase regulator Glc8 in vivo.

The Journal of biological chemistry - 3 Jan 2003

Tan Yves S H, Morcos Paul A, Cannon John F

Abstract excerpt

The budding yeast Glc7 serine/threonine protein phosphatase-1 is regulated by Glc8, the yeast ortholog of mammalian phosphatase inhibitor-2. In this work, we demonstrated that similarly to inhibitor-2, Glc8 function is regulated by phosphorylation. The cyclin-dependent protein kinase, Pho85, in conjunction with the related cyclins Pcl6 and Pcl7 comprise the major Glc8 kinase in vivo and in vitro. Several glc7...

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Identifiers

PMID: 12407105
DOI: 10.1074/jbc.M208058200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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