Article
C-C chemokine receptor 2 and C-C chemokine receptor 5 genotypes in patients treated for chronic hepatitis C virus infection.
Immunologic research - 1 Jan 2002
Dorak M Tevfik, Folayan Gbolahan O, Niwas Santosh, van Leeuwen Dirk J, Yee Leland J, Tang Jianming, Kaslow Richard A
Abstract excerpt
We explored the influence of the major CCR5 promoter or coding region variants as haplotypes and genotypes in a cohort of 250 chronically infected HCV patients receiving combined interferon/ ribavirin therapy. No haplotype, including the D32-bearing haplotype (G*2) reportedly associated in homozygotes with high HCV viral load (VL), showed a similar effect. Patients with genotype C/G*2 showed slightly lower median...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
