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Article

Wnt-4 deficiency alters mouse adrenal cortex function, reducing aldosterone production.

Endocrinology - 1 Nov 2002

Heikkilä Minna, Peltoketo Hellevi, Leppäluoto Juhani, Ilves Mika, Vuolteenaho Olli, Vainio Seppo

Abstract excerpt

Wnt-4 is a signaling factor with multiple roles in organogenesis, a deficiency that leads to abnormal development of the kidney, pituitary gland, female reproductive system, and mammary gland. Wnt-4 is expressed in the cortical region of the developing adrenal gland from embryonic d 11.5 onward, especially in the outermost part. Expression of Cyp11B2 and preadipocyte factor 1 is lowered in the glands of Wnt-4...

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Source

Identifiers

PMID: 12399432
DOI: 10.1210/en.2002-220275

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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