Article
Histologic activity of childhood chronic hepatitis B related to viremia levels, genotypes, mutations, and epidemiologic factors.
Journal of pediatric gastroenterology and nutrition - 1 Oct 2002
Söderström Ann, Norkrans Gunnar, Conradi Nils, Krantz Marie, Horal Peter, Lindh Magnus
Abstract excerpt
BACKGROUND: Despite high viral load, children with chronic hepatitis B virus (HBV) infection may lack significant biochemical signs of liver dysfunction. Failure to develop abnormal liver chemistriesis is probably due to immunologic hyporeactivity. Despite the absence of biochemical abnormalities in these patients, there is still a risk for long-term complications. The pathogenic importance of viral load and...
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