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Article

Relationships and distinctions in iron-regulatory networks responding to interrelated signals

21 Apr 2003

Abstract excerpt

Specialized cDNA-based microarrays (IronChips) were developed to investigate complex physiological gene-regulatory patterns in iron metabolism. Approximately 115 human cDNAs were strategically selected to represent genes involved either in iron metabolism or in interlinked pathways (eg, oxidative stress, nitric oxide [NO] metabolism, or copper metabolism), and were immobilized on glass slides. HeLa cells were...

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PMID: 12393473
DOI: 10.1182/blood-2002-07-2140

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