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Article

Vitamin E deficiency and metabolic deficits in neuronal ceroid lipofuscinosis described by bioinformatics.

Physiological genomics - 3 Dec 2002

Griffin J L, Muller D, Woograsingh R, Jowatt V, Hindmarsh A, Nicholson J K, Martin J E

Abstract excerpt

The mnd mouse, a model of neuronal ceroid lipofusinosis (NCL), has a profound vitamin E deficiency in sera and brain, associated with cerebral deterioration characteristic of NCL. In this study, the vitamin E deficiency is corrected using dietary supplementation. However, the histopathological fe...

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Identifiers

PMID: 12388797
DOI: 10.1152/physiolgenomics.00100.2002

Genes

NCL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12388797-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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