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Article

From genes to systems: new global strategies for the characterization of NCL biology.

Biochimica et biophysica acta - 1 Oct 2006

Jalanko Anu, Tyynelä Jaana, Peltonen Leena

Abstract excerpt

Neuronal ceroid lipofuscinoses (NCL) are rare neurological disorders with a uniform phenotype, caused by mutations in seven known genes. NCL provide a unique model to characterize molecular pathways critical for normal neuronal development and pathological neuronal degeneration. Systems biology based approach utilizes the rapidly developing tools of genomics, proteomics, lipidomics and metabolomics and aims at...

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Source

Identifiers

PMID: 17045465
DOI: 10.1016/j.bbadis.2006.09.001

Genes

NCL
CLN3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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