Article
Human papillomavirus type 16 is episomal and a high viral load may be correlated to better prognosis in tonsillar cancer
6 Sept 2002
Abstract excerpt
The aim of our study was to investigate the physical state and the viral load of HPV-16 in tonsillar cancer and to correlate these findings with clinical outcome. To distinguish between integrated and episomal forms of HPV, 22 fresh-frozen tonsillar cancer samples were analysed by a method based on restriction enzyme cleavage, ligation and PCR (rliPCR). HPV-16 was detected in 11/22 and HPV-33 in 1/22 of the...
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