Article
Prevalence of high-risk human papillomavirus infection and cancer gene mutations in nonmalignant tonsils.
Oral oncology - 1 Oct 2017
Ilmarinen Taru, Munne Pauliina, Hagström Jaana, Haglund Caj, Auvinen Eeva, Virtanen Elina I, Haesevoets Annick, Speel Ernst J M, Aaltonen Leena-Maija
Abstract excerpt
OBJECTIVES: To analyze the prevalence of high-risk HPV (human papillomavirus) and genetic alterations in nonmalignant tonsils. METHODS: We collected benign fresh tonsillar tissue specimens from 477 patients undergoing tonsillectomy because of chronic tonsillitis or tonsillar hypertrophy in 2012 (Group A, n=237) and in 2015 (Group B, n=240). Luminex xMAP technique served to detect E6/E7 DNA from 16 different...
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