Article
Alteration of the microRNA expression profile in familial Mediterranean fever patients.
Clinical and experimental rheumatology - 1 Jan 2000
Akkaya-Ulum Yeliz Z, Balci-Peynircioglu Banu, Karadag Omer, Eroglu Fehime K, Kalyoncu Umut, Kiraz Sedat, Ertenli Ali Ihsan, Özen Seza, Yilmaz Engin
Abstract excerpt
OBJECTIVES: Phenotypic heterogeneity in familial Mediterranean fever (FMF) disease indicated that FMF is not a simple monogenic disease. Therefore it has been suggested that epigenetic factors can be one of the reason for the variations. We undertook this study to test potential involvement of miRNAs in the pathogenesis of FMF. METHODS: miRNA array was performed on whole blood RNA samples from 6 healthy controls...
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