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New Insights into the Genetics of Familial Chromaffin Cell Tumors

1 Sept 2002

Abstract excerpt

We review genetic aspects and recent advances in our understanding of the molecular pathogenesis of familial chromaffin cell tumors (pheochromocytoma, paraganglioma). About 10 percent of pheochromocytomas are familial and occur as part of multiple endocrine neoplasia type 2 (MEN 2), von Hippel-Lindau (VHL) disease, and neurofibromatosis type 1 (NF 1). A subset of paragangliomas, tumors that can also produce and...

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PMID: 12381538
DOI: 10.1111/j.1749-6632.2002.tb04409.x

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