Article
Synergistic activity of the ninth and tenth FIII domains of human fibronectin depends upon structural stability.
The Journal of biological chemistry - 3 Jan 2003
Altroff Harri, Choulier Laurence, Mardon Helen J
Abstract excerpt
The ninth and tenth FIII domains (FIII9-10) of human fibronectin act in synergy to promote cell adhesion via the interaction with integrin receptors. Here we describe the functional and structural properties of a set of recombinant FIII9-10 mutants containing various alanine substitutions within...
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