Article
Identification of an antigenic epitope for helper T lymphocytes from carcinoembryonic antigen.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Oct 2002
Kobayashi Hiroya, Omiya Ryusuke, Ruiz Marta, Huarte Eduardo, Sarobe Pablo, Lasarte Juan José, Herraiz Maite, Sangro Bruno, Prieto Jesús, Borras-Cuesta Francisco, Celis Esteban
Abstract excerpt
PURPOSE: The product of the carcinoembryonic antigen (CEA) gene is an attractive candidate for T-cell-based immunotherapy because it is frequently expressed in epithelial solid carcinomas. Although many CEA peptide epitopes capable of stimulating CTLs have been identified, no MHC class II-restric...
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