Article
In vitro properties of small ruminant lentivirus genotype E.
Virology - 5 Feb 2011
Juganaru M, Reina R, Bertolotti L, Stella M C, Profiti M, Armentano M, Bollo E, Amorena B, Rosati S
Abstract excerpt
Small ruminant lentivirus genotype E lacks the dUTPase subunit and vpr-like gene. Two strains (Roccaverano and Seui) with identical genetic organization have been described, with the env HV1-HV2 domains being the most divergent. Although dUTPase and vpr-like deletions have been involved in the RT fidelity in non dividing cells, both strains were able to replicate efficiently in blood derived macrophages (BDM),...
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