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Article

Mutation analysis of the STK11/LKB1 gene and clinical characteristics of an Australian series of Peutz-Jeghers syndrome patients.

Clinical genetics - 1 Oct 2002

Scott R J, Crooks R, Meldrum C J, Thomas L, Smith C J A, Mowat D, McPhillips M, Spigelman A D

Abstract excerpt

Peutz-Jeghers syndrome (PJS) is a rare cancer predisposition, which is characterized by the presence of hamartomatous polyposis and mucocutaneous pigmentation. A significant proportion of both familial and sporadic forms of this disorder are associated with mutations in the STK11 (serine/threonin...

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Source

Identifiers

PMID: 12372054
DOI: 10.1034/j.1399-0004.2002.620405.x

Genes

STK11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12372054-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Mutation analysis of the STK11/LKB1 gene and clinical characteristics of an Australian series of Peutz-Jeghers syndrome patients.PMID 12372054Read ↗

Molecular and clinical characteristics in 46 families affected with Peutz-Jeghers syndrome.Semantic proximity Read ↗

Further observations on LKB1/STK11 status and cancer risk in Peutz-Jeghers syndrome.Semantic proximity Read ↗

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STK11/LKB1 germline mutations are not identified in most Peutz-Jeghers syndrome patients.Semantic proximity Read ↗

Somatic mutations in the Peutz-Jeghers (LKB1/STKII) gene in sporadic malignant melanomas.Semantic proximity Read ↗

A novel mutation in STK11 gene is associated with Peutz-Jeghers Syndrome in Indian patients.Semantic proximity Read ↗

An updated mutation spectrum in an Australian series of PJS patients provides further evidence for only one gene locus.Semantic proximity Read ↗

Germline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancers.Semantic proximity Read ↗

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