Article
Characterisation of tumoral markers correlated with ErbB2 (HER2/Neu) overexpression and metastasis in breast cancer.
2008-09-01
Abstract excerpt
The receptor tyrosine kinase ErbB2 (HER2/neu) is overexpressed in ~30% of breast cancers and is associated with poor prognosis and an increased likelihood of metastasis. Clinical treatments such as trastuzumab are effective in less than 35% of women diagnosed as ErbB2-positive, highlighting the necessity of searching for novel targets and alternative therapies. Herein, a proteomic screening strategy combining quan...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- d65ac8eb-901a-534e-9f72-b949a004634b
- DOI
- 10.1002/prca.200780020