Article
Animal models of autoimmunity.
Clinics in liver disease - 1 Aug 2002
Howell Charles D
Abstract excerpt
Although several mouse models of AIH have been described, no model is ideal. Indeed, the disease is self-limited in each model, and none is associated with significant liver fibrosis or progression to cirrhosis. Nevertheless, these models should be useful for testing different hypotheses regarding the initiation of AIH. Still, each model poses unique limitations. The EAIH model initiated by immunization with...
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