Article
[Analysis of mutation sites of BRCA1 gene in Chinese patients with breast cancer].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Oct 2002
Ke Yuxiong, Wang Xufen, Feng Meiguang, Wei Candong, Jiang Zhengwen, Jin Li, Lu Daru
Abstract excerpt
OBJECTIVE: To detect the mutation sites of exons 2, 20, 11A and 11B in Chinese patients with breast cancer. METHODS: A total of 86 patients with breast cancer without blood relationship were randomly selected. Polymerase chain reaction (PCR) and double-strand DNA direct sequencing were applied. RESULTS: No mutations, especially deletions were found in exons 2, 20 and 11 with carefully checking the sequencing...
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