Article
[Analysis of the mutation of BRCA1 gene in 70 Uigur women breast cancer patients in Xinjiang].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Jun 2007
Fu Xin-ge, Li Feng, Wang Zhen-hua, Hu Wen-hao, Mikai Re-mu, Jiang Jin-fang, Li Hong-an, Li Li, Zheng Yu-qin, Shen Xi-hua, Pang Li-juan
Abstract excerpt
OBJECTIVE: To analyze the mutations of BRCA1 in breast cancer patients of Uigur women in Xinjiang. METHODS: By using single strand conformation polymorphism (SSCP) and DNA sequencing, BRCA1 mutations were detected in 70 Uigur women breast cancer cases and 32 cases of benign breast diseases and non-tumor tissue next to carcinoma. RESULTS: (1) 12 new loci of BRCA1 gene mutation were detected firstly in 70 Uigur...
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