Article
Possible association between genetic variability at the apolipoprotein(a) locus and Alzheimer's disease in apolipoprotein E2 carriers.
Neuroscience letters - 4 Oct 2002
Compton Danielle, Wavrant DeVriéze Fabienne, Petersen Ronald C, Tangalos Eric, Li Ling, Hardy John
Abstract excerpt
Apolipoprotein(a) (Apo(a)) is a glycoprotein that is linked by a disulfide bond to apolipoprotein B on low density lipoprotein particles to form lipoprotein(a) (Lp(a)). High plasma levels of Lp(a) are thought to contribute directly to the development of atherosclerosis. We tested a variant (T3888P) located in the Kringle-IV region of Apo(a) in a case-control series. Overall, there were no differences between case...
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