Article
[Maturity-onset diabetes of the young--MODY. Molecular-genetic, pathophysiological and clinical characteristics].
Ugeskrift for laeger - 8 Apr 2002
Hansen Torben, Urhammer Søren A, Pedersen Oluf Borbye
Abstract excerpt
Maturity-onset diabetes of the young (MODY) is a genetically and clinically heterogeneous subtype of type 2 diabetes characterised by an early onset, an autosomal dominant inheritance, and a primary defect in insulin secretion. MODY comprises 2-5% of cases of type 2 diabetes. So far, six MODY genes have been identified (MODY1-6): hepatocyte nuclear factor (HNF-4 alpha), glucokinase, HNF-1 alpha, HNF-1 beta,...
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