Article
Increased brain size and glial cell number in CD81-null mice.
The Journal of comparative neurology - 4 Nov 2002
Geisert Eldon E, Williams Robert W, Geisert Grace R, Fan Liying, Asbury Andrew M, Maecker Holden T, Deng Jun, Levy Shoshana
Abstract excerpt
A key issue in the development of the central nervous system (CNS) is understanding the molecular mechanisms regulating cell number. The present study examines the role of CD81 (previously known as TAPA, the target of the antiproliferative antibody) in the control of brain size and glial cell number. CD81 is a member of the tetraspanin family of proteins. This group of small membrane proteins is associated with...
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