Article
Analysis of IL1 gene polymorphisms and transcript levels in periodontal and chronic kidney disease.
Cytokine - 1 Oct 2012
Braosi Ana Paula Ribeiro, de Souza Cleber Machado, Luczyszyn Sônia Mara, Dirschnabel Acir José, Claudino Marcela, Olandoski Márcia, Probst Christian Macagnan, Garlet Gustavo Pompermaier, Pecoits-Filho Roberto, Trevilatto Paula Cristina
Abstract excerpt
UNLABELLED: Chronic kidney disease (CKD) and periodontitis (PD) are complex inflammatory disturbances, influenced by genetic factors. Interleukin (IL)-1 genes code for inflammatory mediators involved in the physiopathogenesis of both diseases. Functional polymorphisms in IL1 genes modulate cytokine levels and have been associated with susceptibility to immune-inflammatory conditions. OBJECTIVES: The aim of this...
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