Analysis of IL1 gene polymorphisms and transcript levels in periodontal and chronic kidney disease.

doi:10.1016/j.cyto.2012.06.006

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Analysis of IL1 gene polymorphisms and transcript levels in periodontal and chronic kidney disease.

Cytokine - 1 Oct 2012

Braosi Ana Paula Ribeiro, de Souza Cleber Machado, Luczyszyn Sônia Mara, Dirschnabel Acir José, Claudino Marcela, Olandoski Márcia, Probst Christian Macagnan, Garlet Gustavo Pompermaier, Pecoits-Filho Roberto, Trevilatto Paula Cristina

Abstract excerpt

UNLABELLED: Chronic kidney disease (CKD) and periodontitis (PD) are complex inflammatory disturbances, influenced by genetic factors. Interleukin (IL)-1 genes code for inflammatory mediators involved in the physiopathogenesis of both diseases. Functional polymorphisms in IL1 genes modulate cytokine levels and have been associated with susceptibility to immune-inflammatory conditions. OBJECTIVES: The aim of this...

Topics

Adult
Aged
Alleles
Analysis of Variance
Chi-Square Distribution
Female
Gene Expression
Gene Frequency
Genetic Predisposition to Disease
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Haplotypes

Humans

Interleukin 1 Receptor Antagonist Protein

Interleukin-1

Interleukin-1alpha

Interleukin-1beta

Male

Middle Aged

Source

Open in PubMed

Identifiers

PMID: 22795294
DOI: 10.1016/j.cyto.2012.06.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-22795294-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of IL1 gene polymorphisms and transcript levels in periodontal and chronic kidney disease.PMID 22795294Read ↗

Association of IL1 gene polymorphisms with chronic periodontitis in Brazilians.Semantic proximity Read ↗

Interleukin-1 gene cluster polymorphisms associated with periodontal disease in type 2 diabetes.Semantic proximity Read ↗

Polymorphic regions in the interleukin-1 gene and susceptibility to chronic periodontitis: a genetic association study.Semantic proximity Read ↗

Polymorphisms within the IL-1 gene cluster: effects on cytokine profiles in peripheral blood and whole blood cell cultures of patients with aggressive periodontitis, juvenile idiopathic arthritis, and rheumatoid arthritis.Semantic proximity Read ↗

Study of IL4-590C/T and IL6-174G/C Gene Polymorphisms in Type 2 Diabetic Patients With Chronic Kidney Disease in North Indian Population.Semantic proximity Read ↗

[Risk factors in adult periodontitis: polymorphism in the interleukin-1 gene family].Semantic proximity Read ↗

IL4 gene VNTR polymorphism in chronic periodontitis in end-stage renal disease patients.Semantic proximity Read ↗

Investigation of the interleukin-1 gene cluster polymorphisms in Jordanian patients with chronic and aggressive periodontitis.Semantic proximity Read ↗

Association of the IL-1RN2 allele with periodontal diseases.Semantic proximity Read ↗

Polymorphisms of the Interleukin-1 Gene Family, Oral Microbial Pathogens, and Smoking in Adult PeriodontitisSemantic proximity Read ↗

Cytokine genotype distribution in patients with periodontal disease and rheumatoid arthritis or diabetes mellitus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.