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Article

Detection of a case of chronic myeloid leukaemia with deletions at the t(9;22) translocation breakpoints by a genome-wide non-invasive prenatal test.

Prenatal diagnosis - 1 Aug 2016

Janssens Katrien, Deiteren Kathleen, Verlinden Anke, Rooms Liesbeth, Beckers Sigri, Holmgren Philip, Vermeulen Katrien, Maes Marie-Berthe, Mortier Geert, Blaumeiser Bettina

Abstract excerpt

OBJECTIVE: Non-invasive prenatal tests (NIPTs) interrogating the complete genome are able to detect not only fetal trisomy 13, 18 or 21 but additionally provide information on other (sub)chromosomal aberrations that can be fetal or maternal in origin. We demonstrate that in a subset of cases, this information is clinically relevant and should be reported to ensure adequate follow-up. METHOD: Genome-wide NIPT was...

Read the complete abstract on PubMed

Topics

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Share to Chromosomes, Human, Pair 22
Share to Chromosomes, Human, Pair 9

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fusion Proteins, bcr-abl

Share to Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Share to Pregnancy Complications, Neoplastic

Share to Pregnancy Trimester, First

Share to Prenatal Diagnosis

Share to Translocation, Genetic

Source

Identifiers

PMID: 27293081
DOI: 10.1002/pd.4857

Genes

ABL1
BCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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