Article
Apolipoprotein E epsilon4 and testosterone interact in the risk of Alzheimer's disease in men.
International journal of geriatric psychiatry - 1 Oct 2002
Hogervorst E, Lehmann D J, Warden D R, McBroom J, Smith A D
Abstract excerpt
OBJECTIVES: To assess the association between testosterone levels and APOEepsilon4 in cases with AD and controls. METHOD: We included 61 men with definite or probable Alzheimer's disease (AD) and 55 elderly male controls from the Oxford Project to Investigate Memory and Ageing (OPTIMA). Testosterone was measured using a competitive enzyme immunoassay (Bayer). RESULTS: We found that both low serum testosterone and...
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